Using both mouse experimental colitis models and IBD patient biopsies, here the authors implicate increased tissue factor activity on colitogenic T cells as a potential link. Although effector ...

Meanwhile, a reserve population of progenitor-like T RM cells continues to lie low in the crypts. "These cells can replenish the pool of effector T cells, so the immune system keeps them as back ...

We are interested in further understanding the molecular and cellular mechanisms involved in NK cell development, effector function, and generation of memory. We have recently demonstrated that ...