The eukaryotic cell, the most significant increase in complexity in the history of life's evolution on Earth, emerged as a phase transition and unlocked the path toward other major transitions ...

The eukaryotic cell, the most significant increase in complexity in the history of life's evolution on Earth, emerged as a phase transition and unlocked the path toward other major transitions ...

This review discusses the molecular mechanisms that impact both processes in eukaryotic cells of different origins. The emerging global picture suggests evolutionarily conserved regulation and ...

The predominant signaling pathways leading to dysregulation of translational control in cancer are the PI3K-AKT-mTORC1, RAS-RAF-MAPK, and MYC pathways, which all converge on eukaryotic translation ...

aDepartment of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China bCAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for ...

Translation initiation of eukaryotic mRNAs typically occurs by cap-dependent ribosome scanning mechanism. However, certain mRNAs are translated by ribosome assembly at internal ribosome entry sites ...

Table 1: Differences between prokaryotes and eukaryotes. In eukaryotic cells, transcription and translation are not coupled. Transcription occurs in the nucleus, producing mRNA. The mRNA then exits ...

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Since translation mechanisms are conserved, researchers began to wonder if a similar phenomenon could be seen in the cells of eukaryotic organisms, such as plants, fungi, and animals. Recently ...

eukaryotic translation initiation factor 4E; mSIN1, mammalian stress-activated MAPK- interacting protein 1; Rictor, rapamycin insensitive companion of mTOR; Atg-1, autophagy-related protein 1; 4E-BP1, ...

It consists of two major steps: transcription and translation. These steps differ in prokaryotic and eukaryotic cells. Here, we will focus on eukaryotic cells. Transcription is the synthesis of any ...