The table below is a review of notable updates that occurred in January 2025 for investigational products in development.

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase first identified in a chromosomal translocation associated with some anaplastic large cell lymphomas (ALCL), a subset of T-cell non ...

Defactinib is an oral, selective inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase-2 (Pyk2), the two members of the focal adhesion kinase family of non-receptor protein ...

Avutometinib plus defactinib granted priority review by FDA, under the accelerated approval pathway, for recurrent KRAS mutant LGSOC; PDUFA action date set for June 30, 2025 Potential U.S ...

The secret to robust and reversible underwater adhesion: The answer lies in epidermal growth factor (EGF) domain Date: January 23, 2025 Source: Pohang University of Science & Technology (POSTECH ...

A research team at POSTECH has uncovered the molecular mechanism behind the remarkable underwater adhesion of hairy mussels (Barbatia virescens). Their findings, published in Nature Communications ...