A research team led by Prof. Jiang Yanyi from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has uncovered an important mechanism that enables squamous cell carcinoma (SCC ...

The discovery of a well-preserved fossil is helping researchers learn more about an iconic Jurassic-period dinosaur.

A European research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating Ch ...

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

In today’s fast-paced world, joint pain has become a common concern among individuals of all ages, significantly impacting quality of life and overall well-being. Many struggle with everyday ...

Ancient skin sported intricately patterned scales Focusing on chondrocytes ... irrespective of their vastly different looks and functions. By poring over DNA sequences of zebrafish and human ...

Objectives Interleukin (IL)-17 signalling has been shown to be a key regulator of disease in ankylosing spondylitis (AS) with several IL-17 blockers currently clinically approved. Despite this, the ...

Conclusions These findings indicate that knockdown of Kdm6b in chondrocytes leads to abnormal cartilage development and accelerated OA progression via inhibition of the anabolic metabolism of ...

Objective To investigate the role and mechanistic pathway of Rac1 involvement in pathological changes of OA chondrocytes in vitro and OA development in vivo, as well as to develop a strategy of ...

Most neurons that carry signals regarding movement and higher-level functions, such as thinking and reading, are myelinated. Neurons that control feelings of pain and temperature are sometimes ...

Recently, human fibrin was used as a scaffold to culture pediatric auricular chondrocytes to engineer elastic cartilage. Gene expression studies demonstrated that the engineered cartilage ...