Diseases caused by Candida are among the most common fungal infections worldwide. The new guideline was developed over four years by a team of more than one hundred experts from 35 countries.

Aspergillus ... Antifungal drugs target molecules in the fungal cell wall, a flexible but rigid outer layer that provides the cell protection. By rupturing the protective structure, the drugs ...

Human fungal pathogens exemplify a severe threat to health due to their complex infection strategies and the host's immune system's failure to eradicate ...

Evidence for resistance is growing Several antifungal resistance mechanisms are now known, including: drug efflux, alterations in drug targets, changes in cell membrane and lipid composition ...

Fungal diseases such as Aspergillus fumigatus, which affects the lungs, and Candida ... without harming human cells.

In addition, Candida species cause a variety of mucosal and superficial skin infections that affect many people. Until recent years, the armamentarium of antifungal agents for management of IFDs ...

This guideline establishes new standards for managing fungal infections ... such as resistance to common antifungals and the increasing spread of Candida auris, a multi-resistant pathogen.

Evidence for resistance is growing Several antifungal resistance mechanisms are now known, including: drug efflux, alterations in drug targets, changes in cell membrane and lipid composition ...