Cancer Research20d
An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer
1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...
The EMBO Journal29d
RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Small GTPase RHEB is a well-known mTORC1 ...
The EMBO Journal29d
Two FAM134B isoforms differentially regulate ER dynamics during myogenesis
FAM134B2 lacks the first hairpin structure of the reticulon homology domain but retains the LC3-interacting region (LIR) domain, enabling it to function as an ER-phagy receptor. Proper ER membrane ...