As more people receive genetic testing after a cancer diagnosis, newer variants have been identified that increase the risk ...
UCLA Health’s virtual genetic counseling tool has markedly increased the percentage of cancer patients undergoing recommended germline testing through a point-of-care model. Beth Karlan ...
Among the 124 undergoing germline testing based on high risk, their average age was 56 (range 34–77). Again, germline BRCA2 variation predominated, with eight (8%) testing positive, but only one ...
Of those tested, 50 (17%) harbored a germline pathogenic or likely pathogenic variant ... Factors associated with lower testing rates include socioeconomic conditions, the availability of on-site ...
Genetic testing in Breast Cancer can be done by germline and somatic testing. Germline testing examines inherited mutations ...
This qualitative interview study enrolled patients diagnosed with prostate cancer who had been treated at a safety-net hospital and had received a referral for genetic testing in the previous 12 ...
Germline gene therapy and somatic gene therapy are two quite different proposals, and the legitimate concerns and risks of the former should not be used to stall progress on the latter. The ...
In a single test, WGS can detect somatic small variants ... Patients with this cancer type had an earlier cancer onset if they carried predisposing germline variants. “If we could harness that ...
As more people receive genetic testing after a cancer diagnosis, newer variants have been identified that increase risk of ...