and a uracil DNA glycosylase inhibitor. Base editing targeting Arg37 (R37X) exhibited one of the highest editing efficiencies (54%), accompanied only by silent bystander edits and minimal indel ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. DNA nanotechnology utilizes the principle of complementary base ...

While many researchers can design knockdown and knockout methodologies to remove a gene product, this is mainly untrue for new chemical inhibitor designs that empower multifunctional DNA Damage ...