ATP depletion triggers a protein called adenosine monophosphate-activated protein kinase (AMPK). AMPK helps regulate cellular energy and, in this case, flips the “on” switch for another ...

Chorea is a movement disorder that causes involuntary, unpredictable body movements. Symptoms may include fidgeting to severe uncontrolled arm and leg movements. Chorea is a movement disorder that ...

Nodular basal cell carcinoma is one of the three main subtypes of BCC. Nodular BCC is the most common BCC subtype, accounting for over 50% of all BCC cases. These lesions appear as small, dome-shaped ...

dbDNA is uniquely positioned for the rapid, synthetic and scalable manufacture of guanosine monophosphate (GMP) DNA using a small, simple footprint. The technology can also manufacture genes and ...

The cGAS–STING pathway, comprising the main DNA sensor cyclic guanosine monophosphate/adenosine monophosphate synthase (cGAS) and stimulator of IFN genes (STING), is a major pathway that mediates ...

6-thio-deoxyguanosine monophosphate; 6-TdGDP, 6-thio-deoxyguanosine diphosphate; 6-TdGTP, 6-thio-deoxyguanosine triphosphate; TPMT, thiopurine S-methyltransferase; XO, xanthine oxidase; HGPRT, ...

Its product pipeline includes several sGC stimulators, small molecules that act synergistically with nitric oxide on sGC to boost production of cyclic guanosine monophosphate. The company was ...

Tadalafil is an inhibitor of PDE5 (phosphodiesterase-5), which is a factor produced in the lungs that breaks down a molecule called cyclic guanosine monophosphate (GMP). Cyclic GMP causes blood ...