A new study in the Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic acid-inducible gene I ...

A new study in the peer-reviewed Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic ...

Key steps in the life cycle of HCV include entry into the host cell, uncoating of the viral genome, translation of viral proteins, viral genome replication, and the assembly and release of virions.

The hepatitis C virus genome and polyprotein processing. The HCV genome consists of a singlestranded RNA molecule of approximately 9.6kb. The ORF is flanked by 5′ and 3′ NTRs important in ...

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

Broad-Spectrum Antiviral NV-387 Phase II Clinical Trial Responding to MPox Pandemic in Africa, Readying to Tackle Bird Flu ...

Atomwise, a leader in leveraging machine learning and artificial intelligence (ML/AI) to advance small molecule drug discovery, today announced the appointment of Steve Worland, Ph.D. as Chief ...

Victor Albert, professor of biological sciences: "Others, like spruce, pine and poplar, all have genome sequences ... Andrew Talal, professor, Department of Medicine, in referencing hepatitis C virus ...

New challenges in an age of innovation The 2010s have seen the development of innovative new classes of medicines, building on the greater understanding of the body since the genome was first ...

Dec. 16, 2024 — To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of RNA molecules.

Certain viruses have been shown to be vital in the development of various cancers by integrating viral DNA into the host genome and activating viral oncogenes. These viruses include the Human ...

Four unique siRNA duplexes (siGenome, Dharmacon) targeting each of 120 HCV IEGs (Fusco et al ... Sequence information was obtained from the UCSC genome browser. The reporter for each isoform was ...