Furin is identified as the key enzyme responsible for cleaving the apelin precursor. Inhibiting this cleavage could serve as ...

Cancer Prevention Research publishes articles that focus on cancer prevention, preclinical, clinical, and translational research, with special attention given to molecular discoveries and an emphasis ...

Hypoxia inducible factor-1α (HIF1α) is a master driver of stemness in cancer cells under hypoxic conditions. Cell counting, migration, self-renewal ability (cell sphere formation and extreme limiting ...

but remained stable for solar keratoses and nevi (figure 1A–C). Table 1 shows the rate of skin cancer-related conditions managed per 1000 general practice encounters, overall and by different patient ...

The search words include “hypoxia and HIF”, “HIF and breast cancer”, “HIF and angiogenesis and breast ... HIF-1α inhibitors work by suppressing different processes in the HIF pathway: 1) HIF-1a ...

REPORTING LIVE IN E Southbound lanes of Route 1A in East Boston reopened Tuesday afternoon after a bus crashed into a utility pole and brought down three other poles and two transformers.The ...

Colon cancer cases are soaring in young people, alarming experts and leaving doctors scrambling for answers as to why. Now, a study published by a team of international researchers in the journal ...

This interview has been edited for length and clarity, but not his warning: “Hypoxia can be dangerous, and I can’t emphasize that enough. Hypoxia in the extreme can be very detrimental, ...

Although maternal iron imbalance and placental hypoxia are independent contributors to the pathogenesis of preeclampsia, a hypertensive disorder of pregnancy, the mechanisms by which their interaction ...

It was an evening of repeats at the 2A and 1A competitive cheer state championship on Wednesday at UVU. In both 2A and 1A, the same two teams that won the all-girl and co-ed state titles a year ago ...