Recent research has increasingly focused on understanding the dynamics of calcium and its interactions with other signaling molecules, such as inositol trisphosphate (IP3) and nitric oxide (NO ...

(Bottom) tDCS-induced calcium surges are absent in IP3 Receptor 2 knockout mice. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

Classically, the GPCR signaling pathway is considered to ... 1,4,5-triphosphate (IP3). cAMP, calcium and IP3 are the second messengers commonly assessed to follow GPCR activation.