Introduction: Fibrocartilaginous embolism (FCE) is a rare etiology of spinal cord infarction that occurs when nucleus pulposus material from intervertebral discs spontaneously embolizes into a spinal ...

Nucleus pulposus cells were isolated from 8-week-old Sprague-Dawley (SD) rats. Initially, the soft tissue surrounding the tail was carefully dissected to expose the intervertebral disc. The nucleus ...

The functional alteration of nucleus pulposus cells (NPCs) exerts a crucial role in the occurrence and progression of intervertebral disk degeneration (IDD). Circular RNAs and microRNAs (miRs) are ...

Lumbar herniated nucleus pulposus (HNP ... thickening and bulging of the ligamentum flavum, bulging of an intervertebral disc, osteophyte formation, or spondylolisthesis. Symptoms include leg ...

A recent study shows the potential of chitosan hydrogels combined with decellularised nucleus pulposus matrix and growth factor microspheres to prevent intervertebral disc degeneration. 59 This ...

Spinal disorders, particularly those related to intervertebral discs, have become one of the leading causes of disability and chronic pain across the globe. The prosthetic disc nucleus provides a ...

Intrigued by this fact and how it might apply to humans, researchers in Toronto, Canada, decided to conduct a gene expression study on intervertebral discs from canines. Their results, presented ...

Many aspects of the physiology of the intervertebral disc (IVD) show clear diurnal rhythms. However, it is unknown whether IVD tissue contains functional circadian clocks and if so, how their ...