Grey’s Anatomy fans have their theories about which characters died in the hospital explosion — but who does the cast think might not come back for season 22?

Grey's Anatomy, spanning 21 seasons and 448 episodes, is one of the most popular medical dramas of all time.

Former Grey’s Anatomy star Eric Dane has opened up about his struggle with ALS (amyotrophic lateral sclerosis, also known as Lou Gehrig’s disease) after revealing his diagnosis in April.

Jeffrey Dean Morgan Says He's Auditioned 'Zero Times' Since Playing Denny Duquette on Grey's Anatomy (Exclusive) The "Walking Dead" star tells PEOPLE his "whole career launched" in his 40s after ...

"Grey's Anatomy" is not done yet, at least not on streaming. After a successful run on ABC, Season 21 of the longest-running primetime medical drama will be dropping on Netflix this weekend ...

Grey’s Anatomy star Eric Dane opened up about his recent diagnosis with amyotrophic lateral sclerosis (ALS) during an appearance with Good Morning America’s Diane Sawyer. “I wake up every ...

George Takei is targeting President Trump with the ultimate Trekkie insult, calling the commander in chief the “biggest Klingon around.” “Change is constant and change will come,”… ...

'Star Trek' icon George Takei discusses his graphic memoir 'It Rhymes With Takei,' coming out at age 68 and the importance of participating in democracy.

Grey’s Anatomy is known for breaking fans’ hearts with brutal character deaths and tearjerkers, but some episodes are particularly sad.

But what is it about a smile that makes it feel sincere — or fake? The answer lies in a surprising blend of facial anatomy, neurology and emotional authenticity.

Is Grey's Anatomy on tonight? Is Grey's Anatomy Season 21 over? When will Grey's Anatomy return with new episodes? When will Grey's Anatomy Season 21 be on Netflix? Here's everything you need to know.

"Grey's Anatomy" showrunner Meg Marinis tells TheWrap about the Season 21 finale's explosive cliffhanger and more.