Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...

Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery.

Mass General Brigham researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery ...

Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in ...

Complement activation participates in the pathogenesis of a variety of diseases and induces tissue damage. The complement system is activated through three pathways (Figure 1). The classical pathway ...

Jan. 15, 2025 — New observational data and simulation models have confirmed a new type of planet unlike anything found in the Solar System. This provides another piece of the puzzle to ...