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Microglia digest large Alzheimer's plaques by spitting enzymes at them, preclinical study finds"We found that the cells basically attach a lysosome onto a large plaque, and they expel enzymes into the space that can digest the amyloid," said Frederick Maxfield, M.S. '73, Ph.D. '77, the ...
Its hallmarks include tangled clumps of amyloid-beta, a peptide (protein fragment) that aggregates in large plaques, which according to the new study, can seed more protein clusters, creating a wave ...
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