Perfluoroalkyl and polyfluoroalkyl substances (PFAS), a diverse group of synthetic chemicals, are commonly used in numerous ...

Peripheral membrane proteins, for example some signalling proteins, are tethered by an anchor, via a fatty acid, prenyl group, glycophosphatidylinositol (GPI) or a hydrophobic protein patch.

This important study characterizes the mechanics and stability of bolalipids from archaeal membranes using molecular dynamics simulations. A mesoscale model of bolalipids is presented and evaluated ...

The phospholipid bilayer nanodiscs (LNDs), as a rapidly-developing tool ... functions of membrane proteins as well as a versatile delivery vehicle for a variety of hydrophobic and hydrophilic drugs.

The next step is the hydrophobic interactions between the amphipathic domains ... The primary structure of any membrane is the lipid bilayer. Several model systems have been developed to mimic the ...

Department of Chemistry and Biochemistry, Iona University, 715 North Avenue, New Rochelle, New York 10801, United States Artificial Cell Membrane Systems Group, Kanagawa Institute of Industrial ...

4.2. Dimerization of EGFR-ErbB1 TMD in a Lipid Bilayer We applied our algorithm to study the dimerization of the EGFR-ErbB1 TMD. The ErbB family contains receptor tyrosine kinases that have a crucial ...

To induce the folding/insertion of peptide into the membrane lipid bilayer, HCl was added to lower the pH value from 8 to 4. CD signals of gold nanoparticles were taken as baseline signals and were ...