Hepatocellular carcinoma continues to pose a diagnostic challenge, particularly in the setting of underlying pathomorphological changes in the liver due to cirrhosis, steatosis, or steatohepatitis.

In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, researchers have identified a vulnerability that opens ...

First identified by Stevens and Johnson in 1922, SJS and TEN are now recognized as disorders with a continuum of severity, ...

Within cells, ROS can stabilise hypoxia-inducible factors (HIFs), which are important mediators of inflammation. Oesophageal biopsies from patients with acute reflux oesophagitis show increased ...

“These viruses can cause cell death, and chronic infections can lead to scarring, or fibrosis,” says Sudha Kodali, MD, a hepatologist in Sugar Land, Texas, and a volunteer for the American ...

FAIRFIELD, N.J., Jan. 31, 2025 /PRNewswire/ -- American Liver Foundation (ALF) is thrilled to announce the recipients of its prestigious 2024 Liver Scholar and Postdoctoral Research Fellowship Awards.

Interestingly, in liver tissues, there was a slight increase ... diseases with hypoxic conditions as their pathogenesis Hypoxia is a condition in which the supply of oxygen cannot meet cell ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

Akero Therapeutics reported Monday strong results from a nearly two-year, placebo-controlled study showing its drug efruxifermin reversed liver scarring in patients with cirrhosis caused by the ...

Figure 1. During sepsis, liver macrophages (Kupffer cells) in hepatic sinusoids synthesize large amounts of inflammatory cytokines (TNF-α, IL-6, IL-1β) through the TLR4-MyD88/NF-κB pathway. Moreover, ...

To determine cell density for subsequent staining, cell counting was performed using Countess II. Afterwards, cells were fixed and stained with FxCycle™ PI/RNase Staining Solution (Invitrogen) for 30 ...