“So, if you want to study the embryonic development of mammary glands, you can use this system.” To establish mammary organoids, the research team used an approach called curating stem cells to ...

In a first, aging-related gene expression changes in breast tissues are linked to alterations in chromatin accessibility.

Our laboratory’s research is based upon the philosophy that it necessary to first define the mechanisms regulating normal mammary gland development in order to understand the alterations in breast ...

Research in the Lewis lab is focused on the genetic regulation of mammary gland development and early-stage breast cancer. Early detection of breast cancer is widely recognized as a key to effective ...

Researchers at The Jackson Laboratory created an aging breast tissue atlas, revealing how genetic and molecular shifts may ...

LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...

Researchers frequently use organoids derived from mammary glands and tumors to study breast cancer, but they have previously been unable to generate models for the development of mammary tissue. Using ...

A team of US researchers has developed a new genetic model for breast cancer that could help scientists better understand why and where cancer metastasises. Professor Eran Andrechek from Michigan ...