Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

One group of proteins working in such specialized environments are the membrane receptors, which act like biological "antennas," sensing signals from the environment and triggering cellular responses.

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with variations in receptor function.

Using protein structure prediction tools, researchers have uncovered receptor structure-function relationships to improve ...

Integral membrane proteins such as receptors and ion channels span the membrane. Peripheral membrane proteins, for example some signalling proteins, are tethered by an anchor, via a fatty acid ...

To switch on the cell death signal, just 15% of all CD95 receptors on the cell membrane need to bind in twos or threes around ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Researchers at the Center for Life Sciences at the Paul Scherrer Institute PSI have for the first time identified structural ...

HHMI researchers discover that protein related to snake venom toxin ... physiologists had told us they weren’t really sure that a membrane-bound molecule like lynx-1 could even access the receptor,” ...