Feedback regulation of the nociceptive signal occurs via a midbrain reaching spino-bulbo-spinal loop, which releases serotonin onto excitatory receptors in the dorsal horn. The integrity of this ...

Striatal dopamine (DA) release regulates reward-related learning and behavioural activation and is believed to consist of a short-lived phasic and continuous tonic component. Here, we build a ...

The inferior colliculus (IC) and the locus coeruleus (LC) are two midbrain nuclei that integrate multimodal ... to a major extent, the dorsal and lateral part of the IC and the intercollicular ...

Background: Parkinson’s disease (PD) is a progressive neurodegenerative condition that primarily affects motor functions; it is caused by the loss of midbrain dopaminergic (mDA) neurons. The ...

Zoe Strimpel on the joys of seeing the world through the eyes of a nine-month-old.

A daytime morning “chatfest” featuring a team of dynamic and diverse women, discussing the most exciting events of the day.

Strong evidence supports the view this is encoded by fast (phasic) changes in dopamine levels and drives learning processes to influence future behaviour. Patient: “I used to sew. I used to sew all my ...

Correspondence to Dr Cecilia Marelli, Department of Neurology, Expert Center for Neurogenetic Diseases and Adult Mitochondrial and Metabolic Diseases, Gui de Chauliac University Hospital, Montpellier, ...

ENEOS to sell over 460 million JXAM shares, raising $3bn to fuel hydrogen and synthetic fuel projects in Japan’s biggest ...