Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...

The translocase of the outer membrane (TOM) complex is the main entry ... target the hydrophobic precursors to mitochondria and into the inner membrane 5,7. A carrier protein contains ...

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Mitochondria, often described as cellular power plants, generate energy through a sequence called the electron transport chain, comprising various protein complexes ... than 20.5 million deaths ...

Analogous to chromosomal DNA that wraps around histone proteins to fit in the nucleus, mtDNA molecules are compacted into mtDNA-protein complexes termed nucleoids. Mitochondrial nucleoid proteins ...

The "power plants" of living cells, the mitochondria, probably evolved through ... evolved from this early partnership—and hence all complex living organisms, including humans.

However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

These changes to mitochondrial RNAs involve the site-specific insertion of over 1300 ‘extra’ nucleotides, targeted base conversions, and the removal and replacement of nucleotides at the 5’ end of ...