A mother has told of her heartbreak at losing both her sons to mitochondrial disease, and her attempts to raise awareness of ...

for the treatment of pyruvate dehydrogenase complex deficiency (PDCD). There are currently no FDA-approved treatments for PDCD, a mitochondrial disorder of carbohydrate oxidation that leads to ...

The complex interplay between vascular contractility and ... followed by reduced α‐smooth muscle actin expression. Mechanistically, PGRN deficiency suppressed mitochondrial respiration, induced ...

The study shows that mitochondria do more than provide energy; they play an active role in modulating the immune response.

This deficiency triggers the acquisition of reactive iron ... and ferroptosis induced by cysteine starvation or erastin et al. (134). Inhibition of mitochondrial complex III function with S3QEL ...

With the increasing prevalence of hair loss and thinning hair, many individuals are seeking effective and natural solutions ...

In the absence of CARD9, mitochondrial dysfunction increases mitochondrial ... susceptibility to intestinal inflammation and fungal infection in a context of Card9 deficiency in vivo. Understanding ...

DCA will be used with a proprietary genetic test to treat an orphan pediatric mitochondrial disease, Pyruvate Dehydrogenase Complex Deficiency (PDCD) 1. The FDA granted Priority Review for the NDA and ...

The Better Results Doug Bates Philosophy In an industry traditionally focused on metrics, such as how much you can lift or the number of squats you perform, Doug Bates offers a different ...