Discovery of new fat cell subtypes in the human body could advance personalized obesity treatment
A new international study led by scientists from Ben-Gurion University of the Negev has characterized the populations of fat ...
Frontiers16d
Ketogenic diet with aerobic exercise can induce fat browning: potential roles of β-hydroxybutyrate
Introduction: Despite evidence suggesting that metabolic intermediates like β-HB influence white adipose tissue (WAT) metabolism, the precise molecular mechanisms remain unclear. The aim of this study ...
C&EN17d
Purple Sweet Potato Ameliorates High-Fat Diet-Induced Visceral Adiposity by Attenuating Inflammation and Promoting Adipocyte Browning
Department of Family and Community Medicine, Chung Shan Medical University Hospital, No. 110, Sec. 1, Jianguo N. Road, South Dist., Taichung City 40221, Taiwan School ...
ahajournals.org19d
Bone Marrow Niche in Cardiometabolic Disease: Mechanisms and Therapeutic Potential
49 Extramedullary hematopoiesis has been observed in tissues such as the liver, spleen, and adipose tissue. In these cases, pathogenic stimuli lead to the recruitment of HSC/HSPCs from the bone marrow ...
Yahoo Finance20d
BioAge Labs Announces Company Updates on APJ, NLRP3, and Platform Programs
RICHMOND, Calif., Jan. 28, 2025 (GLOBE NEWSWIRE) -- BioAge Labs, Inc. ("BioAge", “the Company”), a clinical-stage biopharmaceutical company developing therapeutic ...
manilatimes22d
BioAge Labs Announces Company Updates on APJ, NLRP3, and Platform Programs
Nomination of NLRP3 inhibitor BGE-102 as a development candidate, with initial Ph1 clinical data anticipated by end of 2025 Expansion of discovery efforts based on insights from BioAge's platform, ...
C&EN22d
Strategic Mutations in Designer Native Peptides Combat NLRP3 Inflammasome Activation in Neurodegenerative Disorders
Bioorganic Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur P.O., Bengaluru 560064, Karnataka, India ...
Frontiers23d
5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation
Introduction: Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. NLRP3 inflammasome-driven ...