"We're going to need therapies that can protect against further nephron loss -- SGLT2 inhibitors ... All participants had biopsy-proven IgAN and had an eGFR ≥30 mL/min/1.73m 2.

The approach is an auto-transplant of progenitor cells obtained via kidney biopsy and then reintroduced ... this combination of cells was able to induce new nephron formation, reduce disease ...

Renal hypoplasia, defined as abnormally small kidneys with normal morphology and reduced nephron number, is a common cause of pediatric renal failure and adult-onset disease. Genetic studies ...