Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions ...

Recent scientific advances in bone biology and immunology have greatly expanded our insights into the pathogenesis of osteoporosis. For those with osteoporotic fractures, however, the physical and ...

Osteoporosis is a common complication of many types of liver disease. Research into the pathogenesis of osteoporosis has revealed that the mechanisms of bone loss differ between different types of ...

Osteoporosis is a bone metabolic disorder characterized by decreased bone density and deteriorated microstructure, which increases the risk of fractures. The imbalance between bone formation and bone ...

While factors such as myocardial ischaemia, worsening renal function, volume overload and chronic pulmonary disease may contribute to decompensation, the primary pathophysiology in hypertensive AHF ...

Osteoporosis is a disorder in which loss of bone strength leads to fragility fractures. This review examines the fundamental pathogenetic mechanisms underlying this disorder, which include: (a ...

Organoid Research Center, Institute of Translational Medicine, Shanghai University, Shanghai 200444, People’s Republic of China National Center for Translational Medicine (Shanghai) SHU Branch, ...

Therefore, a better understanding of the pathological signaling pathways and key molecules involved in the pathogenesis of osteoporosis is crucial for the design of therapeutic targets and drug ...

Some people who take epilepsy medicines are at risk of developing osteoporosis. This is a condition that weakens bones, making them more likely to break (fracture). However, some more recent studies ...