PPAR-LXR is a prominent research topic in the use of herbal compounds to treat atherosclerosis by modulating macrophage responses and lipid metabolism. By stimulating the AMPK-PPARγ-LXRα-ABCA1 pathway ...
A subset of these lipids (e.g. oleamide, desmosterol) serve as ligands for nuclear receptors PPAR and LXR, and activation of these receptors occurred specifically during hyperactive IFN signaling in ...
Up till now, the LXR name has been reserved for private islands and palatial hotels. Now it's going to be used for an upmarket farming retreat. Hilton has signed deals for three new hotels in ...
CHIP, Clonal hematopoiesis of indeterminate potential; LXR-alpha, Liver X receptor alpha; PPAR-gamma, Peroxisome-proliferator activated receptor gamma; LDL, Low density lipoprotein; HMGCR, 3-hydroxy-3 ...
Some work as activators, turning genes on, whilst others work as repressors, turning genes off. For example, the transcription factor PPAR alpha is a well-known activator that helps to regulate fat ...
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