jmg.bmj16d
Perturbations of BMP/TGF-β and VEGF/VEGFR signalling pathways in non-syndromic sporadic brain arteriovenous malformations (BAVM)
Pathogenic variants were then studied in vivo using a transgenic zebrafish model. Conclusions Our study highlights the specific role of BMP/TGF-β and VEGF/VEGFR signalling in the aetiology of BAVM and ...
Seeking Alpha27d
Kodiak Sciences: Anti-VEGF Could Win Nicely On Retinal Disorders
For example, KOD’s Tarcocimab Tedromer is an anti-vascular endothelial growth factor [anti-VEGF] antibody biopolymer conjugate that’s currently in Phase 3. This candidate is being tested in ...
C&EN1mon
Extracellular Vesicles Separation and Biomedical Application Based on Affinity Recognition and Antifouling Coating Bifunctional Microsphere
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi’an, Shaanxi Province 710119, P. R. China ...
Frontiers2y
Proteotypic Differences of Follicular-Patterned Thyroid Neoplasms
The diagnosis of follicular-patterned thyroid tumors such as follicular thyroid adenoma (FA), follicular thyroid carcinoma (FTC), and follicular variant of papillary thyroid carcinoma (FvPTC) remains ...
eLife4y
Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells
WNT proteins are secreted symmetry breaking signals that interact with cell surface receptors of the FZD family to regulate a multitude of developmental processes. Studying selectivity between WNTs ...