Oral Wnt secretion inhibitors, anti-RSPO antibodies and a PTK7-targeting antibody-drug-conjugate have been developed, with some in early clinical trials, which may potentially have differential ...
Having creatinine levels in your blood above 1.2 mg/dL for males and 1.0 mg/dL for females may indicate a potential issue with your kidneys, such as an infection or kidney disease. Creatinine is a ...
An EGFR gene mutation is one of the biomarkers a doctor often tests for after confirming a diagnosis of non-small cell lung cancer (NSCLC). Biomarkers can help guide treatment. EGFR mutations ...
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi’an, Shaanxi Province 710119, P. R. China ...
Department of Respiratory and Critical Care Medicine, National Health Commission (NHC) Key Laboratory of Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science ...
2024). At present, 13 bispecific ADCs have been developed, including M1231 designed for EGFR/MUC1, Glofitamab targeting both CD3 and CD20, Blinatumomab targeting CD3 and CD19, CD30 biAb-AATC targeting ...
WNT proteins are secreted symmetry breaking signals that interact with cell surface receptors of the FZD family to regulate a multitude of developmental processes. Studying selectivity between WNTs ...
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