More information: Umakant Sahu et al, Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis, ...

for the treatment of pyruvate dehydrogenase complex deficiency (PDCD). There are currently no FDA-approved treatments for PDCD, a mitochondrial disorder of carbohydrate oxidation that leads to ...

Over a hundred ATP molecules are synthesized from the complete oxidation of one molecule of fatty acid, and almost forty ATP molecules result from amino acid and pyruvate oxidation. Two ATP ...

Saol Therapeutics, a privately held, clinical-stage pharmaceutical company, announced today that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for ...