The researchers explored the association between QTc length and hydroxychloroquine use by these patients, and they adjusted the data for disease-specific characteristics and cardiovascular ...

The researchers found that hydroxychloroquine, when combined with any QTc-prolonging medication, was associated with a comparable QTc length (434 milliseconds; 95% CI, 430-439), compared with ...

New research shows that use of hydroxychloroquine, a generic drug, does not cause any significant differences in QTc length or prolonged QTc, key measures of heart rate, in people with rheumatoid ...

Dr Michele Petri highlights abstracts on systemic lupus erythematosus from ACR 2020, including the effects of hydroxychloroquine on QTc length and use of belimumab and obinutuzumab on renal outcomes.

Table 1 SNPs in cardiac ion channel genes associated with QTc length in healthy Caucasian populations KCNH2 rs1805123 (K897T) and rs3815459 were in moderate LD (D′=−0.60). Haplotype analysis ...

Nov. 6, 2020 — New research shows that use of hydroxychloroquine, a generic drug, does not cause any significant differences in QTc length or prolonged QTc, key measures of heart rate, in people ...

The greatest determinants of QT/QTc prolongation was QT/QTc length at baseline and fever at admission (P = .001). No deaths were reported related to arrhythmias.

Baseline QTc ≥500ms was seen in 25.4% of patients and a follow-up QTc ≥500ms was seen in 48.8% of patients. Where baseline QTc ≥500ms was associated with follow-up QTc ≥500ms, ...

The researchers found that there was no overall higher frequency of QTc >470 milliseconds in the methadone group (6 percent for methadone group versus 5 percent for controls; P = 0.722).

Prolonged QTc, or more than 500 milliseconds, was not associated with arrhythmias or deaths among these patients. The study also did not find any significant interactions between ...