Clinical trials have been pivotal to the improvements in public health and clinical care, leading to many millions of additional years of healthy life globally. Some examples of disease areas in which ...

The challenges of translating neuroprotective interventions with promising efficacy in animal studies into effective treatments for patients with stroke are well documented, with issues including ...

Researchers have found that fewer sessions of higher dose vaginal cuff brachytherapy work just as well as more frequent, lower-dose treatments for endometrial cancer patients.

Abstract: Factor graphs, initially developed as probabilistic graphical models, have been widely employed for solving large-scale inference problems in robotics, particularly in tasks such as pose ...

The ESOPEC trial was a phase 3, investigator-initiated, multicenter, unblinded, randomized, controlled trial conducted at 25 centers in Germany. The trial centers are listed in the Supplementary ...

This study was a multicentre, double blind, randomised, placebo controlled clinical trial conducted in 16 centres in China. Eligible participants were aged 20 to 70 years, had a body mass index ...

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The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Importantly, rates of inclusion of pregnant participants in drug trials have not changed in 15 years, despite calls for greater involvement, the researchers showed in their findings. Randomized ...