Targeting both the antibody-dependent and antibody-independent function of B cells in adult rheumatic disease has led to the advent of B cell targeted therapies in clinical practice. To date, whether ...

It took more than 50 years for Marthe Gautier to set the record straight about her discovery of the genetic cause of Down ...

Persistent skin and throat infections caused by Streptococcus pyogenes can lead to the development of acute rheumatic fever and rheumatic heart disease ... Biofilms are populations of millions of ...

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The initiation of autoimmune disease in experimental animals with a clone of autoreactive T cells supports the idea ... relevance to susceptibility in rheumatic heart disease.

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Rheumatoid arthritis (RA) is an inflammatory rheumatic disease that causes chronic synovial inflammation ... regulate the expression levels of a number of genes that function in a cell-specific manner ...

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1 University of Leeds Leeds Institute of Rheumatic and Musculoskeletal Medicine ... We also confirmed that these entheseal T cells have the capability to secrete pivotal disease-relevant cytokines ...

This study aimed to investigate whether patients using disease-modifying anti-rheumatic drugs (DMARDs ... We also extracted laboratory data (white cell count, haemoglobin and 10 others) at the time of ...