Taking this unique feature of a TMR-labeled aptamer, we described a noncompetitive aptamer-based fluorescence anisotropy assay for detection of small molecules by using ochratoxin A (OTA) as a model.

(D) Fluorescence microscopy images of NHS-rhodamine labeled WT at different protein concentrations in the presence of 22 µM PolyP. The scale bar is 10 µm. (E) Ionic strength dependence of turbidity at ...

Fan and coworkers reported novel multicolor fluorescent Apt–AuNPs for homogeneous detection of small-molecule targets. [45] First, the multicolor dye-labeled aptamers hybridize with DNA strands ...

Abstract: Here, based on the characteristics of Graphene oxide(GO) and SYBR Green I(SGI) dye, an enzyme-free and label-free fluorescent biosensor with signal amplification through DNA strand reaction ...

(2020) An Aptamer Affinity Column for Purification and Enrichment ... (2021) A Simple “Signal off-on” Fluorescence Nanoplatform for the Label-Free Quantification of Exosome-Derived MicroRNA-21 in Lung ...

The aptamer mimics the activity of green fluorescent protein (GFP). In GFP, a beta-barrel (protein sheets intertwined in a cylindrical structure) contains a tightly bound fluorophore that can only ...

Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics. Nature Biotechnology , 2021; DOI: 10.1038/s41587-020-00794-3 Cite This Page : ...

In this approach, the sgRNA scaffold is fused to RNA aptamers including MS2 and PP7 ... Whether the transient transformation of cells with fluorescent RNP complexes could become another option to ...