Pfizer Inc. today announced positive results from the Phase 3 TALAPRO-2 study of TALZENNA® (talazoparib), an oral poly ADP-ribose polymerase (PARP) inhibitor, in combination with XTANDI® (enzalutamide ...

Increased levels of the upstream glycolytic metabolite glyceraldehyde-3-phosphate activates two of ... modifying the enzyme with polymers of ADP-ribose. [46] By inhibiting mitochondrial superoxide ...

The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...

Rock and dust samples brought back to Earth from the asteroid Bennu contain organic matter and a variety of minerals crucial to the emergence of life ...

(−)-Epigallocatechin-3-gallate (EGCG) is the main bioactive catechin in green tea. The antitumor activity of EGCG has been confirmed in various types of cancer, including lung cancer. However, the ...

Dimethyl sulfoxide was obtained from VWR Life Science (Solon, United States). DMEM was purchased from Gibco (Grand Island, NY, United States). Fetal bovine serum was sourced from Biological Industries ...

Adding fluorine to drug molecules can be tricky, but is often worthwhile. Rachel Brazil talks to the chemists trying to tame ...

North West Phosphate received more than $5 million from the Queensland government to accelerate its Paradise South project and bridge a looming job gap. Wheels are turning and dust is flying at an ...

If you've only seen the Hyundai Ioniq 5 in photos, you might think it's a family hatchback. Its looks are deceiving though: this is actually a big electric SUV. Indeed, at 4.6 metres long and 1.6 ...

Read on to learn everything we know about Fallout 5. If you've ever played a Fallout game, you'll know the series revels in its nuclear-ravaged American setting. Fallout games have all been set in ...