Citing "financial pressures" and "rising costs," UC San Diego Health on Monday announced it is laying off 230 of its employees.

The San Diego Sector Border Patrol said agents discovered a drug smuggling tunnel measuring 2,918 feet in total length, connecting San Diego and Tijuana in April.

Luna said San Diego is normally a town where it's challenging to politically activate the masses. “For a politically focused protest, this was the biggest in our history.

A wildfire that erupted Tuesday afternoon in the San Diego County community of Lakeside was threatening structures, prompting mandatory evacuations.

Thousands of people gathered in downtown and other parts of San Diego county Saturday as part of the “No Kings” protests happening nationwide.

The crash comes weeks after a small Cessna crashed into a San Diego neighborhood in foggy weather and killed six people.

In response to San Diego Pride’s decision to keep Kehlani as a headliner despite her repeated promotion of violent, antisemitic rhetoric, all participating Jewish organizations and synagogues ...

Naval Base San Diego has been put under a shelter in place over a reported threat, according to authorities.

On Monday, the San Diego City Council approved a package of changes to the municipal code intended to improve parking management and increase rates.

The prospective buyer of The Headquarters has agreed to pay $34.9 million to acquire the historically designated dining and retail center on San Diego’s downtown waterfront in a transaction that ...

SAN DIEGO (FOX 5/KUSI) — Tens of thousands of runners, including two celebrities, took to the streets of downtown San Diego over the weekend for the 2025 Rock ‘n’ Roll Running Series San Diego.

The co-founder of a music talent agency and two of his colleagues were among those killed after a small plane crashed in a San Diego neighborhood.