Aminoacyl tRNA synthetases (aaRS), enzymes that catalyze the attachment of each amino acid to its cognate tRNA, are such proteins that have acquired new domains and motifs that enable non-canonical ...
In the aminoacyl-tRNA biosynthesis pathway, the levels of 13 proteins, including seryl-tRNA synthetase, leucyl-tRNA synthetase, tyrosyl-tRNA synthetase, threonyl-tRNA synthetase, prolyl-tRNA ...
Different subsets of the tRNA pool in human cells are expressed in different cellular conditions. The ‘proliferation-tRNAs’ are induced upon normal and cancerous cell division, while the ...
In addition to GCN2 activation and reduced total translation, the reduced charging of tRNA Gln in amino-acid-deprived cells also leads to specific depletion of proteins containing polyglutamine tracts ...
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