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The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen.
Numerical simulations confirm the effectiveness of the derived control law and provide insight into the dynamics of the system. These results help establish a theoretical foundation for understanding ...
DNA topoisomerase 1 is an enzyme present in all organisms, essential for cell proliferation. Its function is based on two catalytic steps: firstly, it cuts and then relinks the DNA, thus relaxing ...
Gepotidacin is an oral, first-in-class triazaacenaphthylene antibiotic that inhibits bacterial DNA replication by blocking 2 different type II topoisomerase enzymes. Study participants were ...
In most pathogens, this inhibits 2 different type 2 topoisomerase enzymes, allowing for activity against the target uropathogens and N. gonorrhoeae. This includes those able to resist current ...
AI used to design a multi-step enzyme that can digest some plastics Enzyme mechanisms can be complex, and getting them to work is tricky.
Topoisomerase I poisons work by disrupting the DNA replication process in cells, a critical step for cell division. Normally, the enzyme Topoisomerase enzymes cleave the hypercoiled segments of DNA, ...
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