Researchers at Goethe University, Johannes Gutenberg University Mainz and Kiel University discover possible method for preventing protein aggregates – Cluster4Future PROXIDRUGS research project.

Now, a study from the Indian Institute of Technology Bombay (IIT-B) sheds light on a newly discovered mechanism behind our ...

Researchers at IIT Bombay have discovered an innovative host protein functioning as a miniature predator, targeting and ...

Researchers have discovered a type of "molecular glue" that can be used to inhibit certain pathological protein interactions.

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA ...

Oxford University Innovations Ltd. has synthesized hypoxia-activated proteolysis targeting chimeras (hypoxia-activated PROTACs; HAP-TAC) comprising a hypoxia-activated moiety modified E3 ubiquitin ...

Neddylation is a post-translational modification that conjugates the NEDD8 protein to protein substrates, such as the cullins, which once neddylated join complex to form cullin-RING ubiquitin E3 ...

Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York ...

School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China ...

Taken together, these findings demonstrate that interferon triggers PARP14-mediated ADP-ribosylation in p62 bodies, which requires an active ubiquitin-proteasome system. Interferon induces the ...

The study looked into the difference between those who experience trauma and those who witness traumatic events.