MotoAmerica makes history, becoming the first professional sports organization to implement Abbott Laboratories’ i-STAT TBI blood test for on-site concussion ev ...

Bpgbio Inc. has synthesized bifunctional compounds comprising an E2 ubiquitin ligase binding ligand covalently linked to an estrogen receptor α (ER-α; ESR1) targeting moiety through a linker acting as ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

In this study we have used extensive experimental NMR data, in combination with statistical coil ensemble modeling and small-angle scattering, to analyze the conformational behavior of the protein ...

C4 Therapeutics Inc. has disclosed proteolysis targeting chimera (PROTAC) compounds comprising a cereblon (CRBN) E3 ubiquitin ligase-binding moiety covalently linked to a Raf kinase B (V600E ...

Researchers from Henan Agricultural University discover that the fungus Cryptococcus neoformans causes meningitis by using ...

Among the approximately 30 autophagy‐related (Atg) genes identified so far, there are two ubiquitin‐like proteins, Atg12 and Atg8. Analogous to ubiquitination, Atg12 is conjugated to Atg5 by Atg7—an ...