lupus.bmj24d
Unravelling the TCRβ repertoire: a key to unlocking the immunopathogenesis and precision medicine in SLE
A TRIzol reagent solution of 5 mL was then directly injected into ... Dβ and Jβ germline genes was performed using a locally operated IgBlast program. Non-functional TCRβ VDJ sequences were excluded, ...
C&EN18d
Committee on Analytical Reagents
Our Mission: The ACS Committee on Analytical Reagents is the only committee in the world dedicated to establishing specifications and developing validated test methods for determining the purity of ...
Frontiers10d
Single-cell analysis of graft-infiltrating host cells identifies caspase-1 as a potential therapeutic target for heart transplant rejection
Aims: Understanding the cellular mechanisms underlying early allograft rejection is crucial for the development of effective immunosuppressant strategies. This study aims to investigate the cellular ...
eLife17d
TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders
TCR data was also processed using the CellRanger suite, using the cellranger vdj subcommand. The contig annotation was done with the GRCm38 vdj references provided by 10X Genomics (version 5.0.0).