Alzheimer's disease may damage the brain in two distinct phases, based on new research using sophisticated brain mapping tools. According to researchers who discovered this new view, the first, early phase happens slowly and silently—before people experience memory problems—harming just a few vulnerable cell types.

"The results fundamentally alter scientists' understanding of how Alzheimer's harms the brain," researchers say.

An analysis of the genetic activity of brain cells in individuals who have died with Alzheimer's disease has revealed the condition progresses in two stages; a slow increase in inflammation, followed by a more rapid degeneration.

New research reveals Alzheimer’s disease may damage the brain in two distinct phases, offering new insights for diagnosis and treatment.