Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

SORL1 dysfunction messes with endosomes in neurons, and with lysosomes in microglia.

Butovsky believes xenon has potential as an AD treatment. A Phase 1 clinical trial of xenon at BWH is recruiting healthy elderly volunteers to test safety and effects on immune cells. “I hope this ...

Several types of RNA help regulate gene expression, and a number of these transcripts have been linked to Alzheimer’s disease. However, no one has comprehensively examined how the regulatory RNA ...