This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

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We have all heard of messenger RNA (mRNA) by now, but what about transfer RNA (tRNA)? Well, there is a growing awareness that this emerging technology is capable of a myriad of biological functions ...

Viagra (sildenafil) is an oral drug used to treat erectile dysfunction (ED) that starts working within one hour and can last for around four hours. It was the first drug approved for the use of ED, a ...

Cells were treated with one of three conditions: 22 mM mannitol (osmotic control), 22 mM glucose (high glucose, HG), or 3 µM carboxymethyl lysine-advanced glycation end product (CML-AGE). Treatments ...

Although a cure is not yet available for this disease, there exist methods to manage its signs, like the incorporation of lysine supplements in a regimen to control symptoms. Lysine is an ...

Attach to any inventory to expand its surface area. Great for access in tight spaces and smart setups with threshold switches. Create has dropped support for 1.18 and 1.19 since 0.5.1g. As a result, ...

Introduction: RNA polymerase III (Pol III) is a critical enzymatic complex tasked with the transcription of ubiquitous non-coding RNAs including 5S rRNA and all tRNA genes. Despite the constitutive ...

In particular, using amber suppression for the site-specific incorporation of ncAAs with bioorthogonal reactive groups for click chemistry allows precise protein engineering that is superior to ...