Jul 22, 2019 · In this study, we investigated the optimal extent of LN dissection in GEJ cancer via the analysis of the distribution of lymph node metastasis, prognostic factors and recurrence patterns in GEJ cancer.

In this article, the pattern of lymph node metastasis of GEJAC is reviewed, and the extent and method of lymph node dissection for this tumor are discussed and proposed based on the review. Keywords: Gastroesophageal junction, Adenocarcinoma, Lymph node dissection.

In the present review, we describe the pattern of lymph node metastasis in esophageal cancer and the rate of lymph node metastasis with respect to a lesion's invasion depth. We also clarify the indication for endoscopic resection in esophageal cancer. All lymph node metastases occur along the lymphatic chain.

To determine the optimal treatment for GEJ cancers, identifying the exact tumor location is of great importance because this strongly influences the pattern of lymph node (LN) metastasis.

Aug 1, 2007 · In advanced gastroesophageal junction adenocarcinoma, the high frequency of nodal metastases and the related unfavorable long-term outcome achieved by means of surgical intervention alone are indicative of the need for aggressive multimodal treatment along with surgical intervention to improve long-term results.

Three-field lymph node dissection improves staging accuracy, enhances locoregional disease control and might improve survival in the group of patients with cervical and upper mediastinal metastatic lymph nodal involvement from middle and proximal-third esophageal cancer.

Jul 22, 2019 · Mediastinal lymph node (MLN) metastasis rates among patients with GEJ cancer are reported to be 5-25%. However, survival benefits associated with MLN dissection in GEJ cancer has been a controversial issue, especially in Eastern countries, due to its rarity and potential morbidity.

Introduction: Reported rates of subcarinal lymph node (LN) metastases for esophageal carcinoma vary from 20% to 25% and the relevance of subcarinal lymph node dissection (LND) for gastroesophageal junction (GEJ) adenocarcinoma is poorly defined.

Jan 1, 2007 · En bloc resections and three-field lymphadenectomy are concepts pioneered in the West and East, respectively; both should be performed in specialized centers because such extended lymph node dissection has substantial morbidity rates. Recent focus in research is on refining the indications for these procedures.

Jul 28, 2023 · GEJ cancer treatment requires radical surgical removal of the tumor. The surgical approach, extent of resection of the esophagus and stomach, extent of lymph node dissection, and method of reconstruction are impor.