Merkel cell carcinoma (MCC) is a rare malignant skin neoplasm with the potential for local recurrence, spreading to regional lymph nodes (LNs) and distant metastases. Although it has …

The primary neuroendocrine skin cancer, Merkel cell carcinoma (MCC), has a well-known predilection to metastasize systemically. However, the experience of systemic metastases in …

Background: Merkel cell carcinoma (MCC) is a rare cutaneous malignancy of neuroendocrine origin with a high propensity for lymph node metastasis. Sentinel lymph node (SLN) status is …

Approximately 30% of patients with clinically localized Merkel cell carcinoma (MCC) show nodal involvement on sentinel lymph node biopsy (SLNB). Optimal management of SLNB-positive …

The presence of lymph node metastases was associated with lower MCC-specific death. Further research is warranted in larger cohorts to investigate the impact of the location of metastases …

MCC is divided into stages depending on the size of the primary tumor and extent of disease in the lymph nodes and elsewhere in the body (metastasis). The stage at diagnosis is the major …

Jan 10, 2025 · In time, cancer cells can break away and spread to other parts of the body. When cancer spreads, it's called metastatic cancer. Merkel cell carcinoma is named for the cells …

Merkel cell carcinoma is a rare but aggressive type of skin cancer that can be life-threatening. The cancer affects your skin’s outer layer, or epidermis. It often spreads to lymph nodes and …

Five metastatic patterns were identified: (1) sheet-like (n=38, 59%); (2) non-solid parafollicular (n=4, 6%); (3) sinusoidal, (n=11, 17%); (4) perivascular hilar (n=1, 2%); and (5) rare scattered …

We report three cases of lymph node metastases of MCC with unknown primary sites. Two patients died 17 and 28 months after diagnosis due to brain and pancreatic metastases, …