Apr 18, 2024 · In the context of cancer, MRD-testing attempts to quantify residual cancer cells when the cancer is no longer detectable by conventional methods including blood tests, biopsy …

Jun 27, 2024 · Starting from modestly accurate assays for measurable residual disease (MRD), testing is being used at many centres and available from commercial laboratories. The hope is …

We review concepts underlying MRD-testing and results of studies of MRD-testing in haematological and solid cancers.

Minimal residual disease (MRD) refers to a very small number of residual tumor cells in the body during or after treatment, representing the persistence of the tumor and the possibility of …

Nov 1, 2024 · MRD-testing refers to quantification of residual cancer cells or surrogate markers of cancer cells when there is histological complete remission after a therapy-intervention, i.e. …

We review MRD-testing technologies and evaluate the accuracy of MRD-testing for predicting relapse and the strength of evidence supporting efficacy of MRD-guided therapy. We show …

Apr 18, 2024 · However, an updated critical evaluation of using MRD-tests to predict cancer recurrence and to direct subsequent cancer therapy(ies) is needed. We review concepts …

Affiliations 1 State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & …

There is considerable interest in developing techniques to detect and/or quantify remaining leukaemia cells termed measurable or, less precisely, minimal residual disease (MRD) in …

Sep 13, 2023 · There is considerable interest in tests quantifying remaining leukaemia cells after therapy, termed measurable residual disease (MRD)-tests, to predict therapy outcomes, …