OA-induced steatosis in HepG2 cells resulted in (A) increased lipid peroxidation; (B) decreased cell proliferation, as determined by MTT assay; (C) no changes in ALT level in these cells and …

Jan 30, 2020 · We demonstrated that PA impaired the cell viability and disturbed the lipid metabolism of HepG2 cells (P < 0.01), but OA robustly rescued cells from cell death (P < 0.001).

Oct 9, 2023 · Our study demonstrated that 1) steatosis can be induced by treating HepG2 OOCs with OA or a mixture of OA and PA for 24 h, 2) OOC viability and albumin production were …

Jan 1, 2010 · We demonstrated that in the absence of exogenous inflammatory mediators, OA-induced steatosis was associated with increased production and secretion of tumor necrosis …

Apr 13, 2020 · Lipogenic and inflammatory responses in OA and/or LPS-treated HepG2 cells. The ability of our OA–LPS model to induce lipidosis in HepG2 cells was evaluated by fluorescent …

Oleic and palmitic acids favor different lipid droplet and mitochondria sub-populations with distinct morphological and bioenergetic profiles in HepG2 cells. Both oleic acid (OA) and palmitic acid …

Oct 1, 2021 · Here, we confirmed that EPA reversed PA-induced IR in HepG2 cells and compared the proteomic changes in HepG2 cells after treatment with different free fatty acids (FFAs). A …

Increased autophagy is responsible for OA-induced cell death in HepG2 and SMC7721 cells. In order to find out whether autophagy contributed to the cell death induced by OA in HepG2 and …

May 21, 2011 · To assess whether OA, a monounsaturated fatty acid, would affect autophagy, we first examined the changes in the GFP-LC3 pattern in OA-treated HepG2 cells. HepG2 cells …

Jan 30, 2020 · Palmitic acid induced predominant pyroptosis in HepG2 cells, and ER stress may be responsible for the induction of pyroptosis and subsequent cell death. Monounsaturated …