The mammalian target of rapamycin (mTOR), [5] also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 …

TORC1 in yeast and mammals mediates temporal control of cell growth by regulating several cellular processes, including translation, transcription, ribosome biogenesis, nutrient transport, …

Here, we highlight and summarize the current understanding of how mTOR nucleates distinct multi-protein complexes, how intra- and extracellular signals are processed by the mTOR …

The MTOR gene provides instructions for making a protein called mTOR. Learn about this gene and related health conditions.

Dec 18, 2022 · The mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that regulates multiple processes, including gene transcription, protein synthesis, ribosome …

Jan 5, 2024 · The mTOR signaling pathway is a critical regulator of cellular processes, with wide-reaching implications in health and disease. Understanding its complex regulatory …

Jun 30, 2025 · The mammalian/mechanistic target of rapamycin (mTOR) signaling pathway integrates critical environmental and metabolic cues to regulate immune cell activation, …

Oct 2, 2023 · The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …

Mar 9, 2017 · Here, we review recent advances in our understanding of mTOR function, regulation, and importance in mammalian physiology. We also highlight how the mTOR …

Dec 26, 2019 · mTOR Definition mTOR is a highly conserved serine/threonine-protein kinase enzyme, initially found in mammals. The activity of mTOR protein kinase can be inhibited by a …