Selection of the correct start codon during initiation of translation on the ribosome is a key event in protein synthesis. In eukaryotic initiation, several factors have to function in concert to ensure …

This review discusses some rules for assessing the completeness of a cDNA sequence and identifying the start site for translation. Features commonly invoked-such as an ATG codon in …

Mar 10, 2014 · The context sequence motif surrounding the ATG initiation codon influences mRNA translation efficiency and affects protein production; however, the optimal sequence …

We examined a dataset of highly expressed plant genes to see if they had features conserved downstream of the ATG initiator codon and if such features were in contrast to the genes …

Jun 8, 2021 · An adenine insertion produced a cryptic ATG codon that resulted in disruption of Kozak sequence (G to C at −3 position).

Use 'ATG' only as ORF start codon, or all alternative start codons, corresponding to the selected genetic code, or any sense codon (find all stop-to-stop ORFs)

The accepted model of eukaryotic translation initiation begins with the scanning of the transcript by the pre-initiation complex from the 5′end until an ATG codon with a specific nucleotide (nt) …

May 26, 2015 · Analysis of the annotated genomes found that ATG was the most prevalent translational start codon among Mycoplasma spp. However in Mycoplasma gallisepticum a …

May 7, 2024 · Witmer et al. provide genomic and molecular evidence to demonstrate that Fndc5 (irisin myokine precursor protein) is translated in humans from an overlooked upstream ATG …

Driving higher levels of expression of specific RAN proteins in a particular reading frames with ATG-initiation codon has also been shown to increase cell death and decrease cell viability in …